How Sugar & Processed Foods Impact Your Health | Dr. Robert Lustig

Andrew Huberman · 5.1M views · 2023 · 3:29:21

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Nutrition & diet scienceMedicine & infectious diseasepodcastdated

Why Hacker News recommends it

HN mentions it mostly as a source for the argument that sugar is toxic, though some commenters push back on claims like fructose being addictive.

What it is

A long Huberman Lab podcast episode with Dr. Robert Lustig on the calories-in, calories-out model and how sugar, fructose, fiber and processed foods affect insulin, liver and metabolic health.

Recommended by 2 HN commenters across 2 different months, 2024 to 2026.

What Hacker News said

Strong rec plexman · 2024-01 · on “Reasons to grow and keep big muscles”

Sugar is poison. Check out the latest talk from Dr Robert Lustig [this video] Its a 3.5h video, but roughly sugar is as toxic as alcohol and the food industry is adding it to most products. In short if it has a label (like most processed foods with many ingredients) you should avoid, switch to the ones that don't have (like an apple). This book is also great "The hacking of the American mind" `While researching the toxic and addictive properties of sugar for his New York Times bestseller Fat Chance, Robert Lustig made an alarming discovery—our pursuit of happiness is being subverted by a culture of addiction and depression from which we may never recover. Dopamine is the “reward” neurotransmitter

Recommends dlahoda · 2026-07 · on “Pizza, pasta, potatoes, protein – how Italian children became so overweight”

This explains how sugars and fast carbs can be healthy [this video] Tldr; highly processed food looses vitamins(micro nutrient starvation) and starch/fiber are needed to slow absorption until it gets to bacteria producing drugs(barbiturate and precursors to neuromediators including), and give signals over vagus nerve to head. May be summary of few books from me too. Do not recall. Add on top chewing fibery food takes time, feeling full starts earlier of being full, and saliva ferments help to digest either.

Critical loeg · 2025-01 · on “Type 2 Diabetes and cardiovascular disease attributable to sugar beverages”

[this video] 22:31 - "fructose is addictive" No. [LINK] [LINK] 25:14 - "the fiber is what mitigates the absorption ... that fructose wasn't for you" Not how that works. You absorb the same fructose whether or not it's co-located with fiber. 33:40 - "this whole calories in / calories out makes no sense ... there's no study that actually shows that cutting calories makes a difference" Completely wrong and against the literature. [LINK] 1:00:17 - "fructose causes leaky gut; that causes inflammation of the liver and ultimately systemic inflammation" No. [LINK] 1:31:10 - Asked to explain trend towards obesity over the past 20 years if not the transition away from trans fats. "It's the increase in suga