DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome
Why Hacker News recommends it
Recommended whenever DNA testing, CRISPR or bioweapons come up, often as the talk that made commenters decide to keep their DNA out of databases.
What it is
John Sotos, a physician and former Intel chief medical officer, argues at DEF CON 25 that genetic diseases are exploitable vulnerabilities in the genome. He warns that CRISPR and related tools will make malicious genome hacks and targeted bioweapons feasible.
Recommended by 11 HN commenters across 8 different months, 2017 to 2023.
What Hacker News said
Strong rec patcheudor · 2017-12 · on “New Model Warns About Crispr Gene Drives in the Wild”
John Sotos, Chief Medical Officer of Intel covered the dangers of this technology quite well at DEF CON 25. If you've not seen his talk, watch it now, it's in my top ten of the best talks I've been to in the eleven years I've been going to DEF CON: [this video]
Strong rec detritus · 2018-01 · on “Welcome to Pleistocene Park”
If you're interested in this domain, I'd highly recommend watching the following Defcon Talk from Intel's Chief Medical Officer (who'd've thunkit?) which is illuminating and borderline terrifying.. 'DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome' [this video]
Strong rec globuous · 2018-01 · on “DNA Testing Botched My Family's Heritage”
I always kinda curious about dna heritage testing. Until I saw John Sotos' talk at Def Con 25 [0]. He highly recommands you keep your genome private. And that you only give it away if it is vital (aka you're really sick). The talk is absolutely amazing, probably the most captivating talk I have ever watched (thanks HN commenter that shared it a while ago). But anyway, Sotos specifically tells his audience that, as a security measure, they shouldn't release their dna to heritage services. Because it isn't vital. Anywhi, great talk, highly recommand it although Sotos mentions DNA testing for heritage for a few seconds only, so slightly off topic :) [0] [this video]
Strong rec ghj · 2023-12 · on “23andMe hackers accessed a whole lot of user's personal data”
I remember deciding that I never want to ever have my DNA in any database after watching this talk: DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome (2017): [this video]
Recommends Houshalter · 2017-12 · on “US Federal Ban on Making Lethal Viruses Is Lifted”
This was posted a few days ago. It's a talk about the dangers of man made viruses by Intel's chief medical officer: [this video] 2 minutes in he talks about how a strain of flu escaped from a lab in 1977 and killed (and is still killing) millions of people.
Recommends loeee · 2018-01 · on “Why CRISPR-Edited Food May Be in Supermarkets Sooner Than You Think”
This defcon talk on the some of the ways that gene editing can be used and abused might change your mind. [this video] Weaponized crops aside, it's also worth considering about all of the problems that have arisen with invasive species. What happens if a plant bred for it's resilience begins to choke out other crops? What about the problem of creating mono-cultures, either intentionally or inadvertently? And those are just the obvious examples of what could go wrong. Not to say that there isn't a lot of potential for good with these technologies, but I don't think that companies doing an end run around the USDA, or any other regulatory body that might catch potential problems, is all that harmles
Recommends zawerf · 2018-08 · on “Hackable humans and digital dictators: Q&A with Yuval Noah Harari”
There is a much more convincing talk on the dangers of bioengineering: [this video] News article if you can't watch: [LINK] tl;dr “The reason you haven’t heard much about bioweapons is that they’ve been held back by a pretty severe limitation, which is the potential for blowback." Unlocking the ability to target specific genes will overcome this since the same tech that allows targeting only cancer cell will allow targeting specific groups or individuals. > What, for example, if groups spread their agenda in a very direct way, by literally rewriting DNA to make it impossible to live a life against their credo? Suppose militant vegans wanted to end meat eating: there’s a gene for that. Or imagine
Recommends bgaluszka · 2019-02 · on “CRISPR machines that can wipe out entire species”
You may find interesting this presentation from John Sotos on DEF CON [this video] "Genetic Diseases to Guide Digital Hacks of the Human Genome".